Work

Stimulation of cellular DNA synthesis by wild type and mutant bovine papillomavirus DNA

Year: 1987

Type: article

Abstract: Microinjection of recombinant plasmids containing bovine papillomavirus type 1 DNA into the nuclei of mouse C127 cells results in the stimulation of cellular DNA synthesis. Mutations in the viral E2 gene have no apparent effect on this activity even though the same mutations prevent efficient C127 cell focus formation and inhibit transactivation by this gene.

Source: Biochemical and Biophysical Research Communications

DOI: 10.1016/0006-291x(87)91079-5

Authors: Dariusz Jaskulski, Leszek Kaczmarek, Daniel DiMaio

Institutions: Temple University, Yale University

Language: English

Topic: Cervical Cancer and HPV Research

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

Open Access status: hybrid

Estimated APC paid: $3,110

Funders: National Institute on Aging, National Cancer Institute