Protein Disulfide Isomerase and Assisted Protein Folding
Year: 1997
Type: review
Abstract: The folding protein (and protein folder) is beset with a number of problems in translating the simple instructions encoded by DNA into the complex, three-dimensional structure of a correctly folded protein. Nature has solved these problems in an adequate, if not elegant, fashion, but we are just beginning to understand the variety of strategies that cells use to ensure efficient protein folding. This minireview will focus on several of the more general principles of assisted folding using the folding catalyst, protein disulfide isomerase (PDI),1 as an example.
Source: Journal of Biological Chemistry
Author: Hiram F. Gilbert
Institution: Baylor College of Medicine
Language: English
Topic: Heat shock proteins research
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
Estimated APC paid: $3,430
OpenAlex ID: W2031277486