Gap junctional conductance: comparison of sensitivities to H and Ca ions.
Year: 1982
Type: article
Abstract: One cytoplasmic aspect of the junctional membrane between coupled pairs of Fundulus blastomeres was perfused with solutions of known H and Ca ion concentrations. Conductance of junctional membrane was decreased by either ion. The sensitivity to H ions was about 10,000 times greater than that to Ca ions. The results suggest that junctional conductance can be modulated by changes in H ion concentration near physiological pH, but that unphysiologically high concentrations of Ca ion, such as would be reached only on cell death, are required for comparable changes in junctional conductance.
Authors: D C Spray, J H Stern, A L Harris, M V Bennett
Institutions: Yeshiva University, Rutgers New Jersey Medical School
Language: English
Topic: Connexins and lens biology
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W2031288682