Work

Principles of protein-protein interactions.

Year: 1996

Type: article

Abstract: This review examines protein complexes in the Brookhaven Protein Databank to gain a better understanding of the principles governing the interactions involved in protein-protein recognition. The factors that influence the formation of protein-protein complexes are explored in four different types of protein-protein complexes--homodimeric proteins, heterodimeric proteins, enzyme-inhibitor complexes, and antibody-protein complexes. The comparison between the complexes highlights differences that reflect their biological roles.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.93.1.13

Authors: S Jones, J M Thornton

Institution: University College London

Language: English

Topic: Protein Structure and Dynamics

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2031772330

FWCI: 13.82

Cites: 43

Cited by: 2,716

Related to: 10