Work

Utilizing TH9 cells as a novel therapeutic strategy for malignancies

Year: 2013

Type: article

Abstract: TH9 cells join the ever-growing list of CD4+ T helper subsets and primarily mediate anti-parasite immune responses. We have recently demonstrated that tumor-specific TH9 cells induce a CCL20-CCR6-dependent regulation of DCs while stimulating CD8+ T cell-mediated antitumor immunity. These findings offer a novel immunotherapeutic strategy against cancer.

Source: OncoImmunology

DOI: 10.4161/onci.23084

Authors: Yong Lu, Qing Yi

Institution: The University of Texas MD Anderson Cancer Center

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,913