Work

A Novel 1,2‐Migration of Acyloxy, Phosphatyloxy, and Sulfonyloxy Groups in Allenes: Efficient Synthesis of Tri‐ and Tetrasubstituted Furans

Year: 2004

Type: article

Abstract: Heading south: The 1,2-migration of the acyloxy, phosphatyloxy, and sulfonyloxy groups in allenyl systems has been discovered. This migration, combined with the transition-metal-catalyzed cycloisomerization reaction, leads to the efficient synthesis of tri- and tetrasubstituted acyl-, phosphatyl-, and sulfonyloxy-substituted furans as single regioisomers.

Source: Angewandte Chemie International Edition

DOI: 10.1002/anie.200353535

Authors: Anna W. Sromek, Alexander V. Kel'in, Vladimir Gevorgyan

Institution: University of Illinois Chicago

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: Novel Direct Approaches Toward Bioactive Heterocycles