Work

High Rate of Coronary Artery Abnormalities in Adolescents and Young Adults Infected With Human Immunodeficiency Virus Early in Life

Year: 2011

Type: article

Study design: Observational Study

Abstract: We completed a cross-sectional study of individuals infected with human immunodeficiency virus in early childhood using cardiac magnetic resonance imaging and magnetic resonance angiography. Coronary artery abnormality (CAA) was defined by the presence of luminal narrowing and irregularity of the coronary vessel wall. More than 50% of participants (14/27) had evidence of CAA. Individuals had a high rate of CAA, suggesting possible early atherosclerosis.

Source: The Pediatric Infectious Disease Journal

DOI: 10.1097/inf.0b013e31820f6575

Authors: Irene J. Mikhail, Julia B. Purdy, David S. Dimock, Vijaya M. Thomas, Nancy A. Muldoon, Sarah B. Clauss, Russell R. Cross, Roderic I. Pettigrew, Rohan Hazra, Colleen Hadigan, Ahmed M. Gharib

Institutions: National Institutes of Health, National Institute of Allergy and Infectious Diseases, Children's National, National Institute of Diabetes and Digestive and Kidney Diseases, Eunice Kennedy Shriver National Institute of Child Health and Human Development

Language: English

Topic: HIV-related health complications and treatments

Subfield: Emergency Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, NHLBI Division of Intramural Research

Award: G8838525055

OpenAlex ID: W2032337088

FWCI: 6.289

Cites: 11

Cited by: 36

Related to: 10