Work

Targeted TLR9-activation/STAT3-blocking abrogates immunosuppressive functions of myeloid-derived suppressor cells from late-stage prostate cancer patients

Year: 2014

Type: conference-abstract

Abstract: Meeting abstracts Recent clinical advances underscored that elimination of tumor-induced immunosuppression is prerequisite for successful therapy of advanced human cancers. The myeloid-derived suppressor cells (MDSCs) are one of the major populations limiting T cell-mediated antitumor immune

Source: Journal for ImmunoTherapy of Cancer

DOI: 10.1186/2051-1426-2-s3-p104

Authors: Dewan Md Sakib Hossain, Dayson Moreira, Qifang Zhang, Stephen J Forman, Sumanta Pal, Marcin Kortylewski

Institutions: City Of Hope National Medical Center, City of Hope

Language: English

Topic: Immune cells in cancer

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,490