Recycling and biogenesis of synaptic vesicles
Year: 1994
Type: article
Abstract: Synaptic vesicles are specialized organelles used for the fast, point-to-point signaling typical of the nervous system. Like secretory granules of the classical regulated secretory pathway, synaptic vesicles undergo exocytosis in a Ca2+-dependent fashion. However, synaptic vesicles are also closely related to vesicles involved in the constitutive recycling of membrane components between the plasmalemma and the early endosome. Here we review available information and open questions regarding the biogenesis of synaptic vesicles, their traffic within nerve terminals and their relationship to vesicles of other vesicular pathways to the plasmalemma.
Source: Seminars in Neuroscience
Authors: Peter S. McPherson, Pietro De Camilli
Institutions: Howard Hughes Medical Institute, Yale University
Language: English
Subfield: Cell Biology
Domain: Life Sciences
Open Access status: hybrid
OpenAlex ID: W2033308136