Work

Antithymocyte Globulin in Reduced-Intensity Conditioning Allografting: Is the Benefit Simply in the Eyes of the Transplanter?

Year: 2014

Type: article

Abstract: In the modern era, graft-versus-host disease (GVHD) and associated nonrelapse mortality (NRM) continue to plague allogeneic hematopoietic cell transplantation (allo-HCT) outcomes. A variety of strategies has been developed to prevent GVHD after allo-HCT, including ex vivo or in vivo T cell depletion, pharmacological inhibition of T cell proliferation or trafficking, monoclonal antibodies, and immune-modulation (to name a few), but the best prophylactic modality remains controversial.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2013.12.571

Author: Mehdi Hamadani

Institution: Medical College of Wisconsin

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650