Work

Discovery of the Hybrid Helix and the First DNA-RNA Hybridization

Year: 2006

Type: article

Abstract: Here I describe early research on RNA structure and the discovery of the DNA-RNA hybrid helix, a key component of information transfer. More than 50 years ago it was realized that the interaction between DNA and RNA was at the core of molecular biology. The problem was chemical in nature: could two different types of molecules interact and serve in the transmission of biological information?

Source: Journal of Biological Chemistry

DOI: 10.1074/jbc.x600003200

Author: Alexander Rich

Institution: Massachusetts Institute of Technology

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: hybrid

Estimated APC paid: $3,430

OpenAlex ID: W2033342471

FWCI: 0.951

Cites: 27

Cited by: 35

Related to: 10