Work

CTX-M-2–Producing Salmonella Typhimurium Isolated from Pediatric Patients and Poultry in Brazil

Year: 2009

Type: article

Abstract: Ten Salmonella enterica serovar Typhimurium isolates producing CTX-M-2 extended-spectrum beta-lactamase were identified from clinical and poultry sources in two distant cities in Brazil between 2003 and 2004. They included two isolates from pediatric patients and eight isolates from poultry or its environment. All isolates exhibited coresistance to non-beta-lactam antimicrobials including tetracycline and trimethoprim/sulfamethoxazole. The CTX-M-2 gene was located on transferable plasmids with sizes between 90 and 170 kb that also carried other resistance determinants in some isolates. By pulsed-field gel electrophoresis, the genetic similarity of the isolates including clinical and poultry ones ranged from 89% to 100%.

Source: Microbial Drug Resistance

DOI: 10.1089/mdr.2009.0050

Authors: Sueli A. Fernandes, David L. Paterson, Ângela C. Ghilardi-Rodrigues, Jennifer M. Adams-Haduch, Ana T. Tavechio, Yohei Doi

Institutions: Instituto Adolfo Lutz, The University of Queensland, Royal Brisbane and Women's Hospital, University of Pittsburgh Medical Center

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Molecular Medicine

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Fogarty International Center