Work

Two-Step Synthesis of Furans by Mn(III)-Promoted Annulation of Enol Ethers

Year: 1987

Type: article

Abstract: Enol ethers, β-dicarbonyl compounds and the Mn(III) reagent Mn3O(OAc)7 react under mild conditions to form 1-alkoxy-1.2-dihydrofurans in good (70–98%) yields. The latter are readily converted to furans by acid-catalyzed elimination of ROH.

Source: Chemistry Letters

DOI: 10.1246/cl.1987.223

Authors: E J Corey, Arun K Ghosh

Institution: Harvard University

Language: English

Topic: Organic Chemistry Synthesis Methods

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: National Institute of General Medical Sciences

Award: DESIGN AND SYNTHESIS OF NONPEPTIDE PROTEASE INHIBITORS