Work

Probiotic Therapy in Radiation‐Induced Intestinal Injury and Repair

Year: 2009

Type: article

Abstract: Intestinal injury from ionizing radiation is a clinically important entity, as enteritis symptoms occur commonly after radiotherapy for pelvic malignancies. Preventative or therapeutic options for radiation enteritis are mostly unsatisfactory; however, available data suggests that probiotic bacteria--those which confer health benefit--may have therapeutic value. Previous reports from both human trials and animal models have evaluated various end points for probiotic usage in limiting radiation-associated intestinal damage. Newer data suggests that particular probiotics and/or their secreted or derived bacterial products may have unique radioprotective properties. We will review the area with a focus on new developments surrounding probiotic therapy in radiation-induced intestinal injury and repair.

Source: Annals of the New York Academy of Sciences

DOI: 10.1111/j.1749-6632.2009.04029.x

Authors: Matthew A. Ciorba, William F. Stenson

Institution: Washington University in St. Louis

Language: English

Topic: Probiotics and Fermented Foods

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funder: National Center for Research Resources