Work

Codon usage inPseudomonas aeruginosa

Year: 1988

Type: article

Abstract: We have generated a codon usage table for Pseudomonas aeruginosa. Codon usage in P. aeruginosa is extremely biased. In contrast to E. coli and yeast, P. aeruginosa preferentially uses those codons within a synonymous codon group with the strongest predicted codon-anticodon interaction. We were unable to correlate a particular codon usage pattern with predicted levels of mRNA expressivity. The choice of a third base reflects the high guanine plus cytosine content of the P. aeruginosa genome (67.2%) and cytosine is the preferred nucleotide for the third codon position.

Source: Nucleic Acids Research

DOI: 10.1093/nar/16.19.9323

Authors: Susan E.H. West, Barbara H. Iglewski

Institutions: University of Rochester Medicine, University of Rochester

Language: Yiddish

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funder: National Institute of Allergy and Infectious Diseases

Awards: PSEUDOMONAS AERUGINOSA ELASTASE, ROLE OF EXOENZYME S IN P. AERUGINOSA INFECTIONS