Work

Liver Transplantation with Use of Cyclosporin a and Prednisone

Year: 1981

Type: article

Abstract: THE difficulties in consistently prolonging survival after orthotopic liver transplantation have been documented by us1 and by Calne.2 In this report we describe a new trial of orthotopic liver transplantation in 14 patients who were scheduled to be treated with cyclosporin A and prednisone. Two patients died during the operation. Ten (83 per cent) of the 12 patients who survived surgery and received the drugs are living after eight to 14 1/2 months; another lived for a year, before dying of a recurrence of cholangiocarcinoma.Although longer follow-up periods and more case studies will be required to establish the safety . . .

Source: New England Journal of Medicine

DOI: 10.1056/nejm198107303050507

Authors: Thomas E. Starzl, Göran B. G. Klintmalm, Kendrick A. Porter, Shunzaburo Iwatsuki, Gerhard P. J. Schröter

Language: English

Topic: Organ Transplantation Techniques and Outcomes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institutes of Health, Medical Research Council, National Center for Research Resources

Awards: General Clinical Research Center, General Clinical Research Center