Work

Cysteine Cathepsins in the secretory vesicle produce active peptides: Cathepsin L generates peptide neurotransmitters and cathepsin B produces beta-amyloid of Alzheimer's disease

Year: 2011

Type: review

Source: Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

DOI: 10.1016/j.bbapap.2011.08.015

Authors: Vivian Hook, Lydiane Funkelstein, Jill Wegrzyn, Steven Bark, Mark Kindy, Gregory Hook

Institutions: University of California San Diego, Medical University of South Carolina, Ralph H. Johnson VA Medical Center, American Life Science Pharmaceuticals (United States)

Language: English

Topic: Protease and Inhibitor Mechanisms

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: Alzheimer's Association, National Institutes of Health, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute on Drug Abuse, National Institute of Neurological Disorders and Stroke

Awards: G1047521124, Biosynthesis of Enkephalin Opioid Peptides, G206867548, Sympathetic Neuroeffector Junctions & Blood Pressure, Inhibitors of beta-Amyloid Production in Alzheimer's, Serpin Protease Inhibitors & Opioid Neuropeptides, University of California San Diego Neuroscience Microscopy Imaging Core, G6372628495, Development of E64d for Alzheimer's disease, G7951674230, Cathepsin L in the Biosynthesis of Enkephalins and beta-Endorphin Opioid Peptides, POMC Processing and Beta-Endorphine-Related Opioid Peptides

OpenAlex ID: W2034718998

FWCI: 0.524

Cites: 124

Cited by: 70

Related to: 10