Work

Rapid hybridization kinetics of DNA attached to submkron latex particles

Year: 1987

Type: article

Abstract: We describe a novel method for attaching any DNA molecule to submicron latex beads and characterize the hybridization kinetic properties of these bead-DNA conjugates. The conjugates hybridize to DNA in solution with rates comparable to homogeneous hybridization reactions, are compatible with common hybridization conditions and are conveniently manipulated. They should thus serve as useful reagents for the fractionation and characterization of DNA and RNA.

Source: Nucleic Acids Research

DOI: 10.1093/nar/15.7.2911

Authors: Stanley F. Wolf, Lora Haines, Judith Fisch, Jonathan N. Kremsky, Joseph P. Dougherty, Kenneth Jacobs

Language: English

Topic: Advanced biosensing and bioanalysis techniques

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2034743206

FWCI: 1.479

Cites: 10

Cited by: 106

Related to: 10