Work

G-CSF Mobilization Alone, a Shorter Duration of Neutropenia, and the Rapidity of Engraftment Are Associated with Engraftment Syndrome in Patients Undergoing Autologous PBSCT for Multiple Myeloma

Year: 2012

Type: article

Abstract: Maiolino in 2003 proposed criteria for Engraftment Syndrome (ES). Criteria included non infectious fever plus one (or more) of the following: rash, pulmonary infiltrates, or diarrhea. Clinical practice has since shifted. In the Maiolino series all patients were mobilized with cyclophosphamide (CTX) and G-CSF, while current options include G-CSF, G-CSF plus plerixafor, or CTX with G-CSF. Patients were also treated with G-CSF in the early transplant period. We felt it appropriate to assess our experience with ES in modern patients with multiple myeloma.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2011.12.197

Authors: B. Burnette, A. Dispenzieri, L. Porrata, W. Hogan, S. Holtan

Institutions: Mayo Clinic, Oregon Health & Science University

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650