Work

A Transition to a Compact Form of DNA in Polymer Solutions

Year: 1971

Type: article

Abstract: In the presence of over-threshold concentrations of simple neutral polymers and salts, DNA undergoes a cooperative change in its solution structure. Sedimentation studies at low DNA concentrations show that phage DNA molecules collapse into particles approaching the compactness of the contents of phage heads. The interaction between DNA and polymers is thought to be nonspecifically replusive.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.68.8.1886

Author: L. S. Lerman

Institution: Vanderbilt University

Language: English

Topic: Electrostatics and Colloid Interactions

Subfield: Physical and Theoretical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: green

Funder: U.S. Public Health Service

OpenAlex ID: W2035362991

FWCI: 6.164

Cites: 9

Cited by: 396

Related to: 9