Work

A case control study of cancer of the pancreas

Year: 1973

Type: article

Abstract: A retrospective epidemiological study was undertaken in 100 males and 42 females with adenocarcinoma of the pancreas and 307 sex-, age-, race-, and hospital-matched controls. The results showed that this cancer predominated among males, particularly at ages under 50, and was significantly associated with cigarette smoking. An association to cigar smoking was suggested. Among women, a significant association with early-onset diabetes was found, and there was a suggestive association with a history of cholecystectomy. The epidemiological data along with the pathological data suggested a working hypothesis that the bile may contain carcinogens which would be refluxed into the pancreatic duct exerting a carcinogenic effect.

Source: Cancer

DOI: 10.1002/1097-0142(197303)31:3<641::aid-cncr2820310323>3.0.co;2-1

Authors: Ernest L. Wynder, Kiyohiko Mabuchi, Nobuhiro Maruchi, Joseph G. Fortner

Institutions: Memorial Hospital, Institute for Cancer Prevention, The University of Tokyo, Memorial Hospital

Language: English

Topic: Pancreatic and Hepatic Oncology Research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funder: National Cancer Institute