Work

A quantitative study of magnetization transfer in MAGIC gels

Year: 2003

Type: article

Abstract: Magnetization transfer (MT) has been measured quantitatively as a function of radiation dose in MAGIC polymer gels. The MT rates between the free and immobile macromolecular proton pools (kmr and kfm), and the ratio of the sizes of these coupled proton pools (Pm/Pf), were measured by analysing the response to an inversion recovery sequence. While pm/pf increases linearly with dose, the fast MT rate kmf also increases with dose, unlike previous measurements in BANG gels. This dependence of kmf on dose suggests there are additional factors that modify spin exchange in MAGIC gels as irradiation occurs.

Source: Physics in Medicine and Biology

DOI: 10.1088/0031-9155/48/21/n01

Authors: Daniel F Gochberg, Peter M Fong, John C Gore

Institutions: Vanderbilt University, Yale University

Language: English

Topic: Advanced Radiotherapy Techniques

Subfield: Radiation

Field: Physics and Astronomy

Domain: Physical Sciences

Open Access status: green

Funders: National Cancer Institute, National Institute of Biomedical Imaging and Bioengineering

Awards: G1429969998, Improved polymer gels for radiation dosimetry by MRI, G4498444186, Proton Relaxation and Contrast Mechanisms in MRI