Work

Cell Growth on In Situ Photo-Cross-Linked Electrospun Acrylated Cellulose Acetate Butyrate

Year: 2012

Type: article

Abstract: In this study, electrospinning was combined with UV curing technology for producing in situ photo cross-linked fibers from methacrylated cellulose acetate butyrate (CABIEM). ECV304 and 3T3 cells were seeded on electrospun fibrous scaffolds. Collagen modified CABIEM fibers were also prepared for improving cell adhesion and proliferation. Cross-linking and the morphology of the fibers were characterized by ATR-FTIR spectrometry and environmental scanning electron microscopy (ESEM). The cytotoxicity of the fibers was examined using the MTT cytotoxicity assay. According to the results, electrospun fibrous scaffolds are non-toxic and cell viability depends on the amount of collagen. It was found that cell adhesion and cell growth were enhanced as the collagen percentage was increased.

Source: Journal of Biomaterials Science Polymer Edition

DOI: 10.1163/092050611x566135

Authors: Emrah Çakmakçı, Atilla Güngör, Nilhan Kayaman-Apohan, Serap Erdem Kuruca, Muzaffer Beyza Çetin, Kadriye Akgün Dar

Institutions: Marmara University, Istanbul University

Language: English

Topic: Electrospun Nanofibers in Biomedical Applications

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Türkiye Bilimsel ve Teknolojik Araştırma Kurumu