Work

Determination of Blastoderm Cells in Drosophila melanogaster

Year: 1971

Type: article

Abstract: A method for culturing blastoderm cells of Drosophila in vivo has been developed that allows these cells to differentiate into larval or adult structures. By intermixture of genetically marked cells from bisected and whole embryos, it was shown that blastoderm cells are restricted in their potential for forming adult epidermal structures. Cells isolated from anterior-half embryos are determined for forming head and thoracic structures, whereas cells from posterior-half embryos are determined for forming thoracic and abdominal structures. The specificity of determination and the localization of determinative factors is discussed.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.68.9.2217

Authors: L.-N. Chan, W. Gehring

Institution: Yale University

Language: English

Topic: Developmental Biology and Gene Regulation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

Funders: National Science Foundation, Jane Coffin Childs Memorial Fund for Medical Research, Yale University

OpenAlex ID: W2035545932

FWCI: 5.032

Cites: 20

Cited by: 275

Related to: 10