Work

Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

Year: 2011

Type: article

Source: Nature

DOI: 10.1038/nature10363

Authors: Christian Frezza, Liang Zheng, Ori Folger, Kartik N. Rajagopalan, Elaine D. MacKenzie, Livnat Jerby, Massimo Micaroni, Barbara Chaneton, Julie Adam, Ann Hedley, Gabriela Kalna, Ian P. M. Tomlinson, Patrick J. Pollard, Dave G. Watson, Ralph J. Deberardinis, Tomer Shlomi, Eytan Ruppin, Eyal Gottlieb

Institutions: Cancer Research UK Scotland Institute, Tel Aviv University, The University of Texas Southwestern Medical Center, The University of Queensland, Institute for Molecular Bioscience, University of Oxford, Centre for Human Genetics, University of Strathclyde, Technion – Israel Institute of Technology

Language: English

Topic: Cancer, Hypoxia, and Metabolism

Subfield: Cancer Research

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: Wellcome Trust, Cancer Research UK, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases, Division of Materials Research

Awards: G1927852939, Metabolic regulation in growth factor-dependent cells, G5734609347, Understanding the genetic basis of common human diseases: core funding for the Wellcome Trust Centre for Human Genetics.

OpenAlex ID: W2036181747

FWCI: 14.87

Cites: 25

Cited by: 505

Related to: 10