Work

Preliminary Study of Colistin versus Colistin plus Fosfomycin for Treatment of Carbapenem-Resistant Acinetobacter baumannii Infections

Year: 2014

Type: article

Study designs: Randomized Controlled Trial, Clinical Trial

Abstract: Ninety-four patients infected with carbapenem-resistant Acinetobacter baumannii were randomized to receive colistin alone or colistin plus fosfomycin for 7 to 14 days. The patients who received combination therapy had a significantly more favorable microbiological response and a trend toward more favorable clinical outcomes and lower mortality than those who received colistin alone. (This study has been registered at ClinicalTrials.gov under registration no. NCT01297894.).

Source: Antimicrobial Agents and Chemotherapy

DOI: 10.1128/aac.02435-13

Authors: Rujipas Sirijatuphat, Visanu Thamlikitkul

Institutions: Siriraj Hospital, Mahidol University

Language: English

Topic: Antibiotic Resistance in Bacteria

Subfield: Microbiology (medical)

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funder: Faculty of Medicine Siriraj Hospital, Mahidol University