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Dependency of Blood Flow Velocity in the Middle Cerebral Artery on End-Tidal Carbon Dioxide Partial Pressure—A Transcranial Ultrasound Doppler Study

Year: 1984

Type: article

Abstract: The end-tidal carbon dioxide partial pressure (PCO2) response curves for the flow velocity in the middle cerebral artery were studied in 31 normal subjects with transcranial Doppler techniques. An exponential curve with an exponent of 0.034 mm Hg-1 was found to be a good fit to the recorded data. By means of this relationship, recordings of flow velocity in cerebral arteries can be normalized to a standard value of PCO2. Physiological aspects of cerebrovascular reactivity to PCO2 and the clinical implications of the PCO2 response curve are discussed. The normal material provides a reference for assessing pathological responses.

Source: Journal of Cerebral Blood Flow & Metabolism

DOI: 10.1038/jcbfm.1984.54

Authors: Thomas-Marc Markwalder, Peter Grolimund, Rolf W. Seiler, Fritz Roth, Rune Aaslid

Institutions: University of Bern, Oslo University Hospital

Language: English

Topic: Traumatic Brain Injury and Neurovascular Disturbances

Subfield: Clinical Neurology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2036566782

FWCI: 10.04

Cites: 26

Cited by: 456

Related to: 9