Work

A single fragment of a malaria merozoite surface protein remains on the parasite during red cell invasion and is the target of invasion-inhibiting antibodies.

Year: 1990

Type: article

Abstract: A complex of polypeptides derived from a precursor is present on the surface of the malaria merozoite. During erythrocyte invasion only a small fragment from this complex is retained on the parasite surface and carried into the newly infected red cell. Antibodies to this fragment will interrupt invasion.

Source: The Journal of Experimental Medicine

DOI: 10.1084/jem.172.1.379

Authors: M J Blackman, H G Heidrich, S Donachie, J S McBride, A A Holder

Institution: National Institute for Medical Research

Language: English

Topic: Malaria Research and Control

Subfield: Public Health, Environmental and Occupational Health

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: World Health Organization, Wellcome Trust