Work

Robertsonian metacentrics of the house musk shrew (Suncus murinus, Insectivora, Soricidae) lose the telomeric sequences in the centromeric area.

Year: 2000

Type: article

Abstract: The house musk shrew, Suncus murinus, is polymorphic for five Robertsonian translocations (Rb8.17, 9.13, 10.12, 11.16, 14.15). Fluorescence in situ hybridisation with a biotin-labelled oligonucleotide, (TTAGGG)7, was performed to localise the telomeric DNA sequences at Rb chromosomes of heterozygous shrews. Hybridisation signals were observed at both ends of all chromosomes, but not at the pericentromeric areas of any of the Robertsonian metacentrics. Our results indicate a complete loss of the telomeric sequences at the fusion points of the Rb metacentrics in S. murinus.

Source: Genes & Genetic Systems

DOI: 10.1266/ggs.75.155

Authors: Margarita B. Rogatcheva, Takao Ono, Shin-ichi Sonta, Sen-ichi Oda, Pavel M. Borodin

Institutions: Institute of Cytology and Genetics, Nagoya University, Aichi Human Service Center, Institute for Developmental Research, Universidade Federal do Rio de Janeiro, Novosibirsk State University

Language: English

Topic: Chromosomal and Genetic Variations

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

Open Access status: bronze

Funder: Russian Foundation for Basic Research

OpenAlex ID: W2037320328

FWCI: 1.117

Cites: 29

Cited by: 18

Related to: 10