Work

Fabrication of a Hybrid Microfluidic System Incorporating both Lithographically Patterned Microchannels and a 3D Fiber‐Formed Microfluidic Network

Year: 2012

Type: article

Abstract: A device containing a 3D microchannel network (fabricated using sacrificial melt-spun microfibers) sandwiched between lithographically patterned microfluidic channels offers improved delivery of soluble compounds to a large volume compared to a simple stack of two microfluidic channel layers. With this improved delivery ability comes an increased fluidic resistance due to the tortuous network of small-diameter channels.

Source: Advanced Healthcare Materials

DOI: 10.1002/adhm.201100052

Authors: Leon M. Bellan, Tatiana Kniazeva, Ernest S. Kim, Alla A. Epshteyn, Donald M. Cropek, Robert Langer, Jeffrey T. Borenstein

Institutions: Massachusetts Institute of Technology, Draper Laboratory, United States Army Corps of Engineers, Construction Engineering Research Laboratory

Language: English

Topic: Microfluidic and Capillary Electrophoresis Applications

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

Open Access status: green

Funders: National Science Foundation, Harvard University, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Biomedical Imaging and Bioengineering, Engineer Research and Development Center, Construction Engineering Research Laboratory

Awards: Biomimetic Design and Construction of an Artificial Lung, G1466207048, G1587441952, G3576276198, 3D Microvascular Networks in Biomaterials Fabricated with Sacrificial Structures, G5876064974, NNIN: National Nanotechnology Infrastructure Network, 3D Microvascular Networks in Hydrogels Fabricated with Sacrificial Structures

OpenAlex ID: W2037925390

FWCI: 3.461

Cites: 19

Cited by: 34

Related to: 10