Work

Synthesis of Immunoglobulin Heavy and Light Chains by the Free Ribosomes of a Mouse Plasma Cell Tumor

Year: 1970

Type: article

Abstract: Free and membrane-bound ribosomes have been isolated from a mouse plasma cell tumor secreting immunoglobulins, and allowed to synthesize proteins under cell-free conditions. Analysis of the products of synthesis by autoradiography of immunoelectrophoresis and peptide maps indicates that both types of ribosomes synthesize heavy and light immunoglobulin chains.

Source: Proceedings of the National Academy of Sciences

DOI: 10.1073/pnas.66.2.425

Authors: B. Lisowska-Bernstein, M. E. Lamm, P. Vassalli

Institutions: University of Geneva, New York University

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W2038179393

FWCI: 3.401

Cites: 15

Cited by: 37

Related to: 10