Work

Three-dimensional, automated magnetic biomanipulation with subcellular resolution

Year: 2013

Type: conference-paper

Abstract: In our previous work we introduced the inverted MiniMag, a magnetic manipulation system capable of 5 degree-of-freedom (5-DOF) wireless control of micro- and nano structures. In this work, we implement a depth tracking algorithm to provide feedback on the z-position of manipulated particles in the absence of a side camera. We demonstrate 3D closed-loop servoing of magnetic microbeads along predefined trajectories. We successfully position magnetic microbeads functionalized with antibodies in close proximity to macrophages with sub-cellular resolution and record the phagocytosis of the beads. We also show that the system can be used for 3D targeted microtissue manipulation inside microfabricated devices.

Source: Proceedings - IEEE International Conference on Robotics and Automation/Proceedings

DOI: 10.1109/icra.2013.6630762

Authors: Simone Schurle, Mahmut Selman Sakar, Alessandro Meo, Jens Moller, Bradley E. Kratochvil, Christopher S. Chen, Viola Vogel, Bradley J. Nelson

Institutions: ETH Zurich, Institute of Robotics and Intelligent Systems, University of Pennsylvania

Language: English

Topic: Micro and Nano Robotics

Subfield: Condensed Matter Physics

Field: Physics and Astronomy

Domain: Physical Sciences

Open Access status: green

OpenAlex ID: W2038227745

FWCI: 2.166

Cites: 16

Cited by: 6

Related to: 10