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Enhanced Vβ7 Gene Usage by Intestinal T‐Lymphocytes in Nondiseased Human Gut Moieties

Year: 1995

Type: article

Abstract: T-lymphocytes are present throughout the length of the mucosa of the small and large intestine.Studies of intestinal intraepithelial T-lymphocytes (IEL) suggest that some IEL are derived from the thymus, whereas others might develop in situ.In the human intestinal epithelium, the majority of T-cells express T-cell receptor ( TcR) ap, CD4-CD8+.The intestinal TcR ap repertoire in man appears to contain dominant populations of cells of the same specificity.*We examined the characteristics of TcR p repertoire in nondiseased human large intestine.Fourteen patients 30 25

Source: Annals of the New York Academy of Sciences

DOI: 10.1111/j.1749-6632.1995.tb44543.x

Authors: S. ESIN, V. HODARA, J. GRUNEWALD, M. JEDDI‐TEHRANI, R. ANDERSSON, T. SVENBERG, AND H. WIGZELL

Institutions: Karolinska Institutet, Karolinska University Hospital

Language: English

Topic: T-cell and B-cell Immunology

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: bronze

OpenAlex ID: W2038591947

FWCI:

Cites: 6

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Related to: 10