Work

Seeing is believing: How the MIP-luc mouse can advance the field of islet transplantation and β-cell regeneration

Year: 2010

Type: article

Abstract: In the last five years, bioluminescence has emerged as a vital tool in the non-invasive quantification of beta-cell mass following islet transplantation in murine models. The successes achieved in bioluminescence imaging in islet transplantation has prompted its use in the discipline of beta-cell regeneration. Employing bioluminescence permits quantifying changes in β-cell mass in an individual mouse over time, which can provide valuable insights into the kinetics of beta-cell regeneration.

Source: Islets

DOI: 10.4161/isl.2.4.12028

Authors: Eric Grossman, Jing Tao, Raphael Wilson, Soo-Young Park, Graeme Bell, Anita Chong

Institution: University of Chicago

Language: English

Topic: Pancreatic function and diabetes

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $2,390