Work

Semmelweis’s methodology from the modern stand-point: intervention studies and causal ontology

Year: 2009
Type: article
Abstract: Semmelweis's work predates the discovery of the power of randomization in medicine by almost a century. Although Semmelweis would not have consciously used a randomized controlled trial (RCT), some features of his material-the allocation of patients to the first and second clinics-did involve what was in fact a randomization, though this was not realised at the time. This article begins by explaining why Semmelweis's methodology, nevertheless, did not amount to the use of a RCT. It then shows why it is descriptively and normatively interesting to compare what he did with the modern approach using RCTs. The argumentation centres on causal inferences and the contrast between Semmelweis's causal concept and that deployed by many advocates of RCTs. It is argued that Semmelweis's approach has implications for matters of explanation and medical practice.
Institution: Lund University
Language: English
Open Access status: hybrid
Estimated APC paid: $2,420
OpenAlex ID: W2039514256
FWCI: 12.37
Cites: 26
Cited by: 11
Related to: 10