Indentation Versus Tensile Measurements of Young's Modulus for Soft Biological Tissues
Year: 2011
Type: review
Abstract: In this review, we compare the reported values of Young's modulus (YM) obtained from indentation and tensile deformations of soft biological tissues. When the method of deformation is ignored, YM values for any given tissue typically span several orders of magnitude. If the method of deformation is considered, then a consistent and less ambiguous result emerges. On average, YM values for soft tissues are consistently lower when obtained by indentation deformations. We discuss the implications and potential impact of this finding.
Authors: Clayton T. McKee, Julie A. Last, Paul Russell, Christopher J. Murphy
Language: English
Subfield: Biomedical Engineering
Field: Engineering
Domain: Physical Sciences
Open Access status: green
Funders: American Health Assistance Foundation, Glaucoma Research Foundation, Research to Prevent Blindness, National Institutes of Health, U.S. Public Health Service, National Heart, Lung, and Blood Institute, National Eye Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases
Awards: Mechanotransduction in corneal disorders, Effects of Substratum Topography on Vascular Endothelium, Biophysical Cues and Corneal Wound Healing, Towards a synthetic basement membrane for the corneal epithelium, Role of Biophysical Cues in the Pathogenesis of Glaucoma, Beyond Biomaterials: Engineering the Wound Bed, G7950946143, VISION RESEARCH CORE GRANT
OpenAlex ID: W2039692967