Successful Repair in Utero of a Fetal Diaphragmatic Hernia after Removal of Herniated Viscera from the Left Thorax
Year: 1990
Type: article
Abstract: MOST infants with congenital diaphragmatic hernia die because their lungs are inadequate to support extrauterine life. This remains true despite advances in postnatal care, including preoperative stabilization,1 , 2 pharmacologic treatment of persistent pulmonary hypertension of the newborn,3 , 4 and temporary support with extracorporeal membrane oxygenation.5 , 6 Recently, prenatal diagnosis has allowed us to define the natural history of fetal diaphragmatic hernia better: approximately 75 percent of fetuses with congenital diaphragmatic hernia detected before birth die despite optimal postnatal care.7 8 9 10 11 The neonatal outcome is related to the degree of pulmonary hypoplasia from in utero lung compression, which is determined by the timing and volume . . .
Source: New England Journal of Medicine
Authors: Michael R. Harrison, N. Scott Adzick, Michael T. Longaker, James D. Goldberg, Mark A. Rosen, Roy A. Filly, Mark I. Evans, Mitchell S. Golbus
Language: English
Subfield: Surgery
Field: Medicine
Domain: Health Sciences
Open Access status: bronze
OpenAlex ID: W2040069812