Work

Detection of an NRAS mutation in Erdheim-Chester disease

Year: 2013

Type: article

Abstract: To the editor: In a recent paper in Blood , Haroche et al reported dramatic efficacy of vemurafenib in 3 cases of multisystem and refractory Erdheim-Chester disease (ECD) and Langerhans cell histiocytosis harboring the BRAF V600E mutation.[1][1] The findings of an ∼50% prevalence of BRAF

Source: Blood

DOI: 10.1182/blood-2013-02-482984

Authors: Eli L. Diamond, Omar Abdel-Wahab, Elena Pentsova, Laetitia Borsu, April Chiu, Julie Teruya-Feldstein, David M. Hyman, Marc Rosenblum

Institution: Memorial Sloan Kettering Cancer Center

Language: English

Topic: Histiocytic Disorders and Treatments

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: bronze

Funders: National Institutes of Health, National Cancer Institute

Award: Origins of BRAF-mutant hematologic malignancies and their therapeutic resistance

OpenAlex ID: W2041213818

FWCI: 7.807

Cites: 5

Cited by: 66

Related to: 10