Work

A Tomato Cysteine Protease Required for Cf-2 -Dependent Disease Resistance and Suppression of Autonecrosis

Year: 2002

Type: article

Abstract: Little is known of how plant disease resistance (R) proteins recognize pathogens and activate plant defenses. Rcr3 is specifically required for the function of Cf-2, a Lycopersicon pimpinellifolium gene bred into cultivated tomato (Lycopersicon esculentum) for resistance to Cladosporium fulvum. Rcr3 encodes a secreted papain-like cysteine endoprotease. Genetic analysis shows Rcr3 is allelic to the L. pimpinellifolium Ne gene, which suppresses the Cf-2-dependent autonecrosis conditioned by its L. esculentum allele, ne (necrosis). Rcr3 alleles from these two species encode proteins that differ by only seven amino acids. Possible roles of Rcr3 in Cf-2-dependent defense and autonecrosis are discussed.

Source: Science

DOI: 10.1126/science.1069288

Authors: Julia Krüger, Colwyn M. Thomas, Catherine Golstein, Mark S. Dixon, Matthew Smoker, Saijun Tang, Lonneke Mulder, Jonathan D. G. Jones

Institutions: John Innes Centre, Sainsbury Laboratory, University of East Anglia, Indiana University Bloomington, Indiana University, University of Southampton, University of North Carolina at Chapel Hill

Language: English

Topic: Plant-Microbe Interactions and Immunity

Subfield: Plant Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDG: Zero hunger

Open Access status: hybrid

OpenAlex ID: W2041400380

FWCI: 24.92

Cites: 21

Cited by: 408

Related to: 10