Work

Mucoadhesive drug delivery system: An overview

Year: 2010

Type: article

Abstract: Mucoadhesive drug delivery systems interact with the mucus layer covering the mucosal epithelial surface, and mucin molecules and increase the residence time of the dosage form at the site of absorption. The drugs which have local action or those which have maximum absorption in gastrointestinal tract (GIT) require increased duration of stay in GIT. Thus, mucoadhesive dosage forms are advantageous in increasing the drug plasma concentrations and also therapeutic activity. In this regard, this review covers the areas of mechanisms and theories of mucoadhesion, factors influencing the mucoadhesive devices and also various mucoadhesive dosage forms.

Source: Journal of Advanced Pharmaceutical Technology amp Research

DOI: 10.4103/0110-5558.76436

Authors: BinduM Boddupalli, ZulkarN.K Mohammed, RavinderA Nath, David Banji

Institutions: Nalanda University, Osmania University

Language: English

Topic: Advanced Drug Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $500