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A genome-wide RNA interference screen reveals an essential CREB3L2-ATF5-MCL1 survival pathway in malignant glioma with therapeutic implications

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Year: 2010
Type: article
Source: Nature Medicine
DOI: 10.1038/nm.2158
Authors: Zhi Sheng, Li Li, Lihua J Zhu, Thomas W Smith, Andrea Demers, Alonzo H Ross, Richard P Moser, Michael R Green
Institutions: Howard Hughes Medical Institute, University of Massachusetts Chan Medical School
Language: English

Topic: Glioma Diagnosis and Treatment
Subfield: Genetics (clinical)
Field: Medicine
Domain: Health Sciences
SDG: Good health and well-being

Open Access status: green

Funders: Howard Hughes Medical Institute, National Institutes of Health, National Cancer Institute, National Institute of Neurological Disorders and Stroke
Awards: Role of Lipocalin 24p3 in Apoptosis and Leukemia, Enhancing glioma chemotherapy by suppressing Notch signaling
OpenAlex ID: W2043258353
FWCI: 5.965
Cites: 51
Cited by: 175
Related to: 10
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