Reduced Oct4 Expression Directs a Robust Pluripotent State with Distinct Signaling Activity and Increased Enhancer Occupancy by Oct4 and Nanog
Work
Year: 2013
Type: article
Abstract: Embryonic stem cell (ESC) pluripotency is governed by a gene regulatory network centered on the transcription factors Oct4 and Nanog. To date, robust self-renewing ESC states have only been obtained t... more
Source: Cell stem cell
Authors Violetta Karwacki-Neisius, Jonathan Göke, Rodrigo Osorno, Florian Halbritter, Jia Hui Ng +9 more
Institutions University of Edinburgh, Genome Institute of Singapore, Nanyang Technological University, National University of Singapore
Cites: 72
Cited by: 184
Related to: 10
FWCI: 10.58
Citation percentile (by year/subfield): 90.86
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: hybrid
APC paid (est): $9,080