Studies on the mechanism of action of synthetic ligands of the vitamin D and estrogen receptor
Year: 2000
Type: dissertation
Abstract: Nuclear hormones play a key role in embtyonic development, growth and\\ndifferentiation of cells and tissues, and in maintenance of homeostasis. They exert\\ntheir action via a large group of nuclear, transctiption factors gathered in the\\nnuclear receptor superfamily. This superfamily consists of\\nreceptors for estrogen, glucocorticoid, mineralocotlicoid, androgen, progesterone,\\nbut also contains receptors for vitamin D, retinoids, fatty acids, and thyroid\\nhormone. Futlhetmore, a large number of so-called orphan receptors are included\\nfor which ligands and functions are at the moment unknown.
Author: Gert-Jan C.M. van den Bemd
Language: English
Subfield: Endocrinology
Domain: Life Sciences
Open Access status: green
OpenAlex ID: W204352806
