Work

Transplantation’s Greatest Challenges: Advances in Chronic Graft-versus-Host Disease

Year: 2007

Type: article

Abstract: Clinical research into chronic graft-versus-host disease (GVHD) lags behind that in other areas in the field. Interest in chronic GVHD has increased significantly in recent years for various reasons, including advances in biotechnology, a perceived increase in the incidence of chronic GVHD, and decreased regimen-related mortality, resulting in a new emphasis on quality of life and absence of disability as endpoints of major significance in transplantation survivors. In this overview, we address 3 key areas related to chronic GVHD that hold the highest promise for major advances in the near future: pathobiology, response criteria, and therapy.

Source: Transplantation and Cellular Therapy

DOI: 10.1016/j.bbmt.2006.10.020

Authors: Warren D. Shlomchik, Stephanie J. Lee, Daniel Couriel, Steven Z. Pavletic

Institutions: Yale University, Fred Hutch Cancer Center, The University of Texas MD Anderson Cancer Center, National Institutes of Health, National Cancer Institute

Language: English

Topic: Hematopoietic Stem Cell Transplantation

Subfield: Hematology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $3,650