Work

Self-assembled hybrid nanoparticles for targeted co-delivery of two drugs into cancer cells

Year: 2014

Type: article

Abstract: A therapeutic aptamer-lipid-poly(lactide-co-glycolic acid) hybrid nanoparticle-based drug delivery system was prepared and characterized. This system can co-deliver two different drugs with distinct solubility and different anticancer mechanisms to target cancer cells with high specificity and efficiency.

Source: Chemical Communications

DOI: 10.1039/c3cc49003c

Authors: Fujian Huang, Mingxu You, Tao Chen, Guizhi Zhu, Haojun Liang, Weihong Tan

Institutions: University of Science and Technology of China, University of Florida, Hunan University, UF Health Cancer Center, State Key Laboratory of Chemobiosensing and Chemometrics, Collaborative Innovation Center of Chemistry for Energy Materials

Language: English

Topic: Nanoparticle-Based Drug Delivery

Subfield: Biomaterials

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Cancer Institute, National Institute of General Medical Sciences

Awards: G268005586, G352705524, G5391260311, Development of molecular probes for biomedical applications

OpenAlex ID: W2043719432

FWCI: 4.319

Cites: 38

Cited by: 83

Related to: 10