Year: 1999
Type: article
Abstract: Diurnal changes in small intestinal intraepithelial lymphocytes (IELs) were examined in 8- to 10-week-old BALB/cA male mice. The ratio of T cell subsets expressing CD8 alpha alpha homodimer/CD8 alpha beta heterodimer was found to be higher in the dark period than that in the light period. Increased expression of Thy-1.2 on gamma delta T cells was also observed in the light period. No significant changes were found in other subsets. This is the first report to document diurnal changes in the small intestinal IELs in mice.
Source: EXPERIMENTAL ANIMALS
Authors: Hodaka SUZUKI, Shinwa SHIBATA, Taichi OKUTANI, Masami SUZUKI, Masaharu NAKAYAMA, Takuya NISHIMURA, Kunio DOI
Language: English
Topic: T-cell and B-cell Immunology
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2043915590