Work

Electrical conduction block in large nerves: High‐frequency current delivery in the nonhuman primate

Year: 2011

Type: article

Abstract: Recent studies have made significant progress toward the clinical implementation of high-frequency conduction block (HFB) of peripheral nerves. However, these studies were performed in small nerves, and questions remain regarding the nature of HFB in large-diameter nerves. This study in nonhuman primates shows reliable conduction block in large-diameter nerves (up to 4.1 mm) with relatively low-threshold current amplitude and only moderate nerve discharge prior to the onset of block.

Source: Muscle & Nerve

DOI: 10.1002/mus.22037

Authors: D. Michael Ackermann, Christian Ethier, Emily L. Foldes, Emily R. Oby, Dustin Tyler, Matt Bauman, Niloy Bhadra, Lee Miller, Kevin L. Kilgore

Institutions: MetroHealth, Cleveland FES Center, Case Western Reserve University, Northwestern University, Louis Stokes Cleveland VA Medical Center

Language: English

Topic: Neuroscience and Neural Engineering

Subfield: Cellular and Molecular Neuroscience

Field: Neuroscience

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: National Institute of Neurological Disorders and Stroke, National Institute of Biomedical Imaging and Bioengineering

Awards: G2518034470, A Novel Waveform for Electrical Nerve Conduction Block, Peripheral Nerve Implementation of Functional Neuroprostheses, G622244862

OpenAlex ID: W2043916316

FWCI: 0.661

Cites: 17

Cited by: 45

Related to: 10