Work

High frequency intravascular photoacoustic (IVPA) imaging for differentiating arterial wall layered structures

Year: 2012

Type: conference-paper

Abstract: Arterial wall is composed of three layers: intima, media and adventitia. Intima-media thickness (IMT) is an important prognostic indicator of atherosclerotic diseases. Although intravascular ultrasound (IVUS) imaging is a commonly used method for delineation of the layered structures, it is inferior to the optical absorption contrast offered by intravascular photoacoustic (IVPA) imaging. We introduce an integrated miniature probe that combines the capabilities of IVUS and IVPA imaging for the evaluation of arterial wall layered structures. Healthy rabbit aorta was imaged ex vivo. IVPA results showed superior contrast over IVUS in identifying the layered structures of arterial wall.

Source: Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE

DOI: 10.1117/12.906581

Authors: Xiang Li, Wei Wei, Qifa Zhou, K. Kirk Shung, Zhongping Chen

Institutions: University of Southern California, Wuhan University, Beckman Laser Institute and Medical Clinic, University of California, Irvine, Edwards Lifesciences (United States)

Language: English

Topic: Photoacoustic and Ultrasonic Imaging

Subfield: Biomedical Engineering

Field: Engineering

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: green

Funder: China Scholarship Council