New Developments in Sleep Research: Molecular Genetics, Gene Expression, and Systems Neurobiology
Year: 2008
Type: article
Abstract: Understanding the mechanisms that underlie the control of sleep and wakefulness is a major research area in neuroscience. This mini-symposium review highlights some recent developments at the gene, molecular, cellular, and systems levels that have advanced this field. The studies discussed below use organisms ranging from flies to humans and focus on the interaction between the sleep homeostatic and circadian systems, the consequences of mutations in genes involved in the circadian clock on sleep timing, the effects of sleep deprivation on brain gene expression, the discovery of "sleep active" neurons in the cerebral cortex, the role of the hypocretin/orexin system in the maintenance of sleep and wakefulness, and the interaction between sleep and learning.
Source: Journal of Neuroscience
Language: English
Subfield: Cognitive Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: hybrid
Funders: Ministry of Education, Culture, Sports, Science and Technology, National Institutes of Health, U.S. Army, National Institute on Aging, National Heart, Lung, and Blood Institute, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, U.S. Army Medical Research Acquisition Activity
Awards: G1498170363, Forced Desynchronization of the Rat Circadian System, G3584421557, G4144523685, Chemical and Genetic Manipulation of Circadian Systems, NEUROBIOLOGICAL STUDIES OF A NOVEL HYPOTHALAMIC PEPTIDE, G5850682332, G6036964498, FUNCTIONAL ANALYSIS OF SLEEP HOMEOSTASIS IN DROSOPHILA, Neural Gene Expression in Sleep Deprivation and Recovery, G8389391685
OpenAlex ID: W2044604367