PROTEIN KINASE B/AKT : Structure, Functions and Regulation. : PROTEİN KİNAZ B/AKT : Yapısı, Fonksiyonları ve Regülasyonu.
Year: 2001
Type: article
Abstract: Protein kinase B (PKB)/Akt is a serine/threonine kinase activated by growth hormones and implicated in prevention of apoptosis, glycogen metabolism and glucose uptake. PKB/Akt regulates a variety of cellular functions including cell survival, cell growth, cell differentiation, cell cycle progression, transcription, translation and cellular metabolism. This review will summarize the structure and functions of PKB/Akt and indicates the evidence that PKB/Akt is an important mediator of physiological effects of insulin and several growth factors and plays a key role in various cellular functions
Authors: Net DAŞ - EVCİMEN, George L. KING
Institutions: Joslin Diabetes Center, Harvard University, Ankara University
Language: Turkish
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: bronze
OpenAlex ID: W2044655814